In this study, the modeling of the transverse connection of fully precast steel-UHPC (Ultra-High-Performance Concrete) lightweight composite bridges were conducted. The transverse connection between precast components plays a critical role in the overall performance and safety of the bridge. To achieve an accurate and reliable simulation of the interface behavior, the cohesive model in ABAQUS was employed, considering both bending-tension and compression-shear behaviors. The parameters of the cohesive model are obtained through interface bending and oblique shear tests on UHPC samples with different surface roughness. By validating the numerical simulation against actual joint tests, the effectiveness and accuracy of the proposed model in capturing the interface behavior of the fully precast steel-UHPC lightweight composite bridge were demonstrated.