Biomaterials and Biomechanics in Bioengineering
Volume 4, Number 1, 2019, pages 001-8
DOI: 10.12989/bme.2019.4.1.001
Effect of polymer concentration in cryogelation of gelatin and poly (vinyl alcohol) scaffolds
Seda Ceylan, Didem Demir, Gülşah Gül and Nimet Bölgen
Abstract
The aim of this study was to investigate the effect of total polymer concentration on the chemical structure, morphology of pores, porosity, swelling ratio, degradation of gelatin-poly (vinyl alcohol) (Gel-PVA) cryogel scaffolds. Porous cryogels were prepared with cryogelation technique by using glutaraldehyde as a crosslinker. Functional group composition of cryogels after crosslinking was investigated by Fourier Transform Infrared (FTIR). The morphology of cryogels was characterized via scanning electron microscopy (SEM) and porosity analysis. All of the cryogels had a porous structure with an average pore size between 45.58
Key Words
gelatin; poly (vinyl alcohol); cryogel; scaffold; tissue engineering
Address
Seda Ceylan, Didem Demir, Gülşah Gül and Nimet Bölgen: Department of Chemical Engineering, Mersin University, Mersin, Turkey
Seda Ceylan: Department of Bioengineering, Adana Science and Technology University, Adana, Turkey