Biomaterials and Biomechanics in Bioengineering

Volume 2, Number 1, 2015, pages 23-32

DOI: 10.12989/bme.2015.2.1.023

Injectable TGF-beta 3-conjugated hyaluronic acid hydrogel for cartilage regeneration

Ki Seong Ko, Jung Seok Lee, Kyung Min Park, Yunki Lee, Dong Hwan Oh, Joo Young Son, Oh Hee Kwon, Min Yong Eom and Ki Dong Park

Abstract

Facile immobilization of growth factors in hyaluronic acid (HA) hydrogels using dual enzymes is reported in the paper. The hydrogels were formed by using horseradish peroxidase (HRP) and hydrogen peroxide (H2O2) and transforming growth factor-

Key Words

biocompatible polymer; biomaterials; biomedical engineering; cartilage; hydrogels

Address

Ki Seong Ko, Jung Seok Lee, Yunki Lee, Dong Hwan Oh, Joo Young Son, Min Yong Eom and Ki Dong Park: Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Republic of Korea Oh Hee Kwon, Ki Dong Park: Deparment of Biomedical Engineering, Ajou University, Suwon 443-749, Republic of Korea Kyung Min Park: Division of Bioengineering, Incheon National University, Incheon 406-772, Republic of Korea