Advances in Nano Research

Volume 19, Number 3, 2025, pages 245-252

DOI: 10.12989/anr.2025.19.3.245

Integrating Nano-AI predictive models for postoperative risk assessment in spinal fusion

Li Chunhui, Zhang Wenjia and Wu Yue

Abstract

Nanotechnology has created new opportunities in precision medicine, providing a chance to monitor the biological signals, molecular markers, and micro-environmental changes at the ultrasensitive level, which occurs before complications. The issue of postoperative complications that arise after performing spinal fusion surgeries is a burning clinical issue, and most of the time, it brings about long-term recovery, increased healthcare expenses, and deteriorated patient outcomes. We suggest the incorporation of nano-enabled AI prediction models in this work that utilizes data collected by nano-sensors, nanomaterials-based diagnostics, and traditional clinical data to improve risk stratification in spinal fusion. Working on a nanoscale, these systems bead on minor physiological changes, including inflammatory biomarkers, metabolic changes, and tissue healing, obscured by conventional techniques. Combined with artificial intelligence, nano-derived datasets offer unmatched granularity, increasing the forecasting performance and allowing timely detection of patients who are at a significant risk of unfavorable events. This model of Nano-AI fills the gap between nano-medicine and computational modeling to provide an innovative solution to customized care postoperative. Finally, the nano-integrated predictive analytics can transform the paradigm of surgical risk assessment, which will inform proactive solutions and support patient safety in sophisticated spinal surgeries.

Key Words

AI-powered risk prediction; machine learning in healthcare; postoperative complications; spinal fusion surgery; surgical outcome optimization

Address

Li Chunhui and Zhang Wenjia: Department of Neurosurgery, The First Hospital of Hunan University of Chinese Medicine, No. 95 Shaoshan Middle Road, Yuhua District, Changsha, Hunan, Postal Code 410021 Wu Yue: Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongti South Road, Chaoyang District, Beijing, 100020