Study of wave propagation along protein intermediate filaments with specialized beam theories
Muhammad Safeer,Sabah Javad,Amien Khadimallah,Muzamal Hussain,Natasha Arooj,Khaled Mohammed Kheder,Rana Muhammad Akram Muntazir
Abstract
This study investigates wave propagation in protein intermediate filaments using advanced beam theories. By formulating a beam model suited to intermediate filaments structural properties, we predict wave speed and frequency, gaining information on their mechanical properties. Our findings reveal intermediate filaments role in cellular mechanics and signaling, providing insight into mechanotransduction and cell-to-cell communication. This study enriches the understanding of cellular biomechanics with relevance to intermediate filaments mutation-related diseases. The phase velocity and frequency versus wave vector are shown in the figures. The comparison of phase velocities versus wave vector and small scale parameter based on non-local Euler Bernoulli and Timoshenko beam model are show in the Tables.
Key Words
atomic force microscopy (AFM); cell mechanics; cytoskeletal dynamics; dispersion relations; mechanotransduction; protein mechanics
Address
Muhammad Safeer, Sabah Javad — Department of Mathematics, University of Poonch Rawalakot 12350, Azad Kashmir, Pakistan
Amien Khadimallah — Prince Sattam Bin Abdulaziz University, College of Engineering, Civil Engineering Department, BP 655, Al-Kharj, 11942, Saudi Arabia
Muzamal Hussain — Department of Physical and Numerical Sciences, University of Rasul, 50400, Mandi Bahaudin, Punjab, Pakistan
Natasha Arooj, Rana Muhammad Akram Muntazir — Department of Mathematics, Lahore Leads University, Lahore
Khaled Mohammed Kheder — Department of Civil Engineering, College of Engineering, King Khalid University, Abha, 61421, Saudi Arabia
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