According to the properties of monoclinic materials, the normal and shear stresses are depending on both normal and shear strains. In the current investigation, the static analysis of monoclinic plates based on three dimensional elasticity theory is investigated. New governing equations and boundary conditions are derived for monoclinic plates and the Differential Quadrature Method (DQM) is used to solve the static problem. In our method of solution, no approximation is used and the DQM is adopted in all directions. By showing the differences between our results and the results for especially orthotropic plates, one can find that it is worth to investigate the monoclinic plates to have more accurate results.