Fiber reinforced polymer (FRP) sheets are the most efficient structural materials in terms of strength to weight ratio and its application in strengthening and retrofitting of a structure or structural elements are inevitable. The performance enhancement of structural elements without increasing the cross sectional area and flexible nature are the major advantages of FRP in retrofitting/strengthening work. This research article presents a detailed study on the inelastic response of conventional and retrofitted Reinforced Concrete (RC) frames using Carbon Fibre Reinforced Polymers (CFRP) and Glass Fiber Reinforced Polymers (GFRP) subjected to quasi-static loading. The hysteretic behaviour, stiffness degradation, energy dissipation and damage index are the parameters employed to analyse the efficacy of FRP strengthening of brick in-filled RC frames. Repair and retrofitting of brick infilled RC frame shows an improved load carrying and damage tolerance capacity than control frame.